The YouTube user Sub2Me4ASub was a relatively famous YouTuber back in the old days of YouTube, although by now he has faded into obscurity. As a result of a copyright strike in 2009, he deleted all of his videos, except his profile icon video. He was briefly suspended, but when his channel was restored, the videos that he deleted were not restored. While he was able to preserve his interactive games by making the StickmanGames channel, most of his videos are still missing to this day.
Update: January, 20th 2016
I have found some of his videos posted to TheStickvidVault channel.